Multiple imputation of missing data using sas kindle edition by berglund, patricia, heeringa, steven g download it once and read it on your kindle device, pc, phones or tablets. This article shows how to perform mean imputation in sas. Introduction to regression procedures tree level 1. We have selected sas for this examplewithout recommending it over other alternativesbecause it is a commonly used generalpurpose statistical. Imputation techniques using sas software for incomplete. For data sets with monotone continuous missing patterns, one can use stochastic regression as discussed earlier. Multiple imputations of categorical variables can be created using the loglinear model schafer 1997, which is implemented in the missing data library of s. The technique consists of substituting m plausible random values for each missing value so as to create m plausible complete versions of the incomplete data set. Missing data, multiple imputation and associated software. One advantage that multiple imputation has over the single imputation and complete case methods is that multiple imputation is flexible and can be used in a wide variety of scenarios. This method involves 3 steps, creating multiple imputed data.
Although these instructions apply most directly to norm, most of the concepts apply to other mi programs as well. Combining survival analysis results after multiple. Using spss to handle missing data university of vermont. Multiple imputation using the fully conditional specification method. These multiply imputed data sets are then analyzed by using standard procedures for complete data. Multiple imputation is the last strategy that will be discussed. The mi procedure in sasstat software is a multiple imputation. Multiple imputation for missing data statistics solutions. Abstract multiple imputation provides a useful strategy for dealing with data sets that have missing values.
I can work this out a bit better when i get sas goingagain. Commonly used techniques for handling missing data, focusing on multiple imputation 2. For data sets with arbitrary missing patterns, it is suggested to use the markov chain monte carlo mcmc method multiple imputation in sas. The resulting m versions of the complete data can then be analyzed by standard completedata methods, and the results combined to produce inferential statements e. The idea of multiple imputation for missing data was first proposed by rubin 1977. Berglund, university of michiganinstitute for social research abstract this presentation emphasizes use of sas 9. Norm, cat, mix, pan sas proc mixed for unbalanced longitudinal data with missing responses does not handle missing covariates, for that refer to. A statistical programming story chris smith, cytel inc. A comparison of multiple imputation methods for missing. It also includes implementation of the algorithm with sas and also challenges attached to it.
The imputation methods were compared on simulated data to assess preciseness. I examine two approaches to multiple imputation that have been incorporated into widely available software. Appropriate multiple imputation and analytic methods are evaluated and demonstrated through an analysis application using longitudinal survey data with missing data issues. I couldnt find an example from sas documentation, though sas did provide. Rpackage norm currently implements this version of multiple imputation schafer, 1997. Likelihood ratio testing after multiple imputation 31 jul 2015, 12. Multiple imputation mi is now widely used to handle missing data in longitudinal studies. Nick has a paper in the american statistician warning about bias in multiple imputation arising from rounding data imputed under a normal assumption. Instead of attempting to estimate each value and using these estimates to predict the parameters, this method draws a random sample of the missing values from its distribution. The author lays out missing data theory in a plain english style that is accessible and precise. Niternumbers the niter option speci es the number of iterations between imputa tions in a single chain. Multiple imputation using sas software yuan journal of. Multiple imputation is a simulationbased approach to the statistical analysis of incomplete data. Find guidance on using sas for multiple imputation and solving common missing data issues.
Use features like bookmarks, note taking and highlighting while reading multiple imputation of. Sas software seems to be lagging the state of the art in imputation by about a decade i think their last serious improvement for imputation was when they added proc mi to sasstat about ten years ago and that methodology had already been around for twenty years at that time. Instead of lling in a single value for each missing value, a multiple imputation procedure replaces each missing value with a set of plausible values that represent the. Combining survival analysis results after multiple imputation of censored event times jonathan l. We are not advocating in favor of any one technique to handle missing data and. Multiple imputation provides a useful strategy for dealing with data sets that have missing values.
In multiple imputation, each missing datum is replaced by m1 simulated values. Just as there are multiple methods of single imputation, there are multiple methods of multiple imputation as well. The scaler values are obtained by using the rubins rule of combining estimates. There is also a very important package in the form of sas macro for multiple imputation using a sequences of regression models. The software also allows for weights to account for sampling design both at level 1 and level 2. Multiple imputation using sas software yang yuan sas institute inc. Below are tables of the means and standard deviations of the four variables in. Retains much of the attractiveness of single imputation from a.
Missing data, multiple imputation and associated software this is. Pdf multiple imputation using sas software researchgate. This tutorial explains multiple imputation and how it works. Multiple imputation of missing data using sas, berglund. It offers practical instruction on the use of sas for multiple imputation and provides numerous. For example, in data derived from surveys, item missing data occurs when a respondent elects not to answer certain questions, resulting in only a dont know or refused response.
In hot deck imputation the missing values are filled in by selecting the values from other records within the survey data. Software for imputation under a multivariate normal model. A commercial software program using the mcmc algorithm is sas proc mi sas, 2011. Appropriate multiple imputation and analytic methods are evaluated and demonstrated through an analysis application using. Multiple imputation using sas software multiple imputation provides a useful strategy for dealing with data sets that have missing values. Software for the handling and imputation of missing data an. There is also a very important package in the form of sas macro for multiple imputation using a. Several mi techniques have been proposed to impute incomplete longitudinal covariates, including standard fully conditional specification fcsstandard and joint multivariate normal imputation jmmvn, which treat repeated measurements as distinct variables, and various extensions based on. Software for the handling and imputation of missing data. Missing data takes many forms and can be attributed to many causes. Multiple imputation mi is an approach for handling missing values in a dataset that allows researchers to use. The m complete data sets are then analyzed by the statistical. Mean imputation replaces missing data in a numerical variable by the mean value of the nonmissing values. Roles of imputation methods for filling the missing values.
This sascallable program is called iveware written by raghunathan et al. Likelihood ratio testing after multiple imputation statalist. Can i get just one p value by combining multiple t test results. Missing data is a common issue, and more often than not, we deal with the matter of missing data in an ad hoc fashion. In sas, proc mi is used to replace missing values with multiple imputation.
Little and rubin 1987, 1990 contend that, with standard statistical techniques, there are. Multiple imputation rubin, 1987 is an alternative missingdata procedure, which has become increasingly popular. In this chapter, i provide stepbystep instructions for performing multiple imputation with schafers 1997 norm 2. With multiple imputation using fcs, a single imputation is conducted during an initial fillin stage. Multiple imputation as a valid way of dealing with. Either the predictors were excluded from the imputation model, in which case we cannot possibly estimate their relation to the outcome reliably, and hence falsely will exclude them. For data sets with monotone missing patterns, either a parametric regression method rubin 1987 that assumes multivariate normality or a nonparametric method that uses. The main goal of multiple imputation is to get robust estimates of your model. This is due to the ability of the multiple imputation process to incorporate statistically sophisticated techniques and draw from. Multiple imputation using sas software journal of statistical. The mi procedure in the sasstat software is a multiple imputation procedure that. Multiple imputation of missing data using sas provides both theoretical background and constructive solutions for those working with incomplete data sets in an engaging exampledriven format. One example where you might run afoul of this is if the data are truly dichotomous or count variables, but you model it as normal either because your software is unable to model dichotomous values directly or because you prefer the theoretical. Proc mi in sas, norm package in r that provide missing data imputation for incomplete multivariate normal data.
With norm a multiple imputation can be implemented. This section describes the methods for multiple imputation that are available in the mi procedure. Instead of filling in a single value for each missing value, a multiple imputation procedure replaces each missing value with a set of plausible values that represent the uncertainty about the right value to. Multiple imputation for continuous and categorical data. Imputing missing data is the act of replacing missing data by nonmissing values. Issues that could arise when these techniques are used 3. Iveware software for sas developed by a group at the university of michigan.
Mi is becoming an increasingly popular method for sensitivity analyses in order to assess the impact of missing data. Missing data techniques with sas idre statistical consulting group to discuss. Norm only allows a few codes for missing, and 999 is one of them, but. Pmms and deltaadjusted pmms by building on existing software packages e. Multiple imputation for missing data is an attractive method for handling missing data in multivariate analysis. In such a case, understanding and accounting for the hierarchical structure of the data can be challenging, and tools. Moscovici, quintilesims, montreal, qc bohdana ratitch, quintilesims, montreal, qc abstract multiple imputation mi is an effective and increasingly popular solution in the handling of missing.
The results from the m complete data sets are com bined for the inference. Multiple imputation for variables following the multivariate normal distribution is supported by programs as norm schafer, 1999, splus 6 for windows 2006, and sas 8. Multiple imputation of incomplete multivariate data under a normal model. Spss will do missing data imputation and analysis, but, at least for me, it takes some getting used to.
In short this is very similar to maximum likelihood. A powerpoint presentation of this webpage can be downloaded here. Multivariate imputation by chained equations in r stef van buuren tno karin groothuisoudshoorn university of twente abstract the r package mice imputes incomplete multivariate data by chained equations. It also presents three statistical drawbacks of mean imputation. Using sas for multiple imputation and analysis of data presents use of sas to address missing data issues and analysis of longitudinal data. Standard statistical procedures for the complete data analysis can then be. Multiple imputation and multiple regression with sas and. This is the result you were looking for, and is comparable to what we found in the last bit of printouts for norm and sas. Multiple imputation an overview sciencedirect topics. Schafer 1997 book on mcmc and multiple imputation for missingdata problems. Implementation of sas proc mi procedure assuming mvn assuming fcs 4. Sas proc mixed for unbalanced longitudinal data with missing responses does not. The mi procedure in the sasstat software is a multi. Multiple imputation mi of missing values in hierarchical data can be tricky when the data do not have a simple twolevel structure.
This is a set of sas macros runs a chained equation. After the initial stage, the variables with missing values are imputed in the order specified on the var statement. The nbiter option speci es the number of burnin iterations before the rst imputation in each chain. These multiply imputed data sets are then analyzed by using standard procedures for complete data and combining the results from these analyses. Introduction to statistical modeling with sas stat software tree level 1.
The purpose of this seminar is to discuss commonly used techniques for handling missing data and common issues that could arise when these techniques are used. I have a question about how to combine student t test results after multiple imputations. Most analysis described in the book are conducted using the wellknown statistical software packages sas and spss, supplemented by norm 2. Multiple imputation with sas deepanshu bhalla 1 comment data science, sas, statistics. The software on this page is available for free download, but is not supported by the methodology centers helpdesk. Vim vim is a package for visualizing and imputing missing data libraryvim. Comparing joint and conditional approaches jonathan kropko university of virginia ben goodrich columbia university. Procedure multiple imputation analyzer proc mianalyze is used after proc mi to be able to combine estimates from the results of analyzing multiply imputed data sets. Multiple imputation for threelevel and crossclassified. The most effective we consider only the multiple imputation techniques 6 that are techniques were applied to diabetes clinical trial data.
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